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© Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institutes of Biomedical Innovation, Health and Nutrition

Publications

2021

  1. Tomiyama, E., Matsuzaki, K., Fujita, K., Shiromizu, T., Narumi, R., Jingushi, K., Koh, Y., Matsushita, M., Nakano, K., Hayashi, Y., Wang, C., Ishizuya, Y., Kato, T., Hatano, K., Kawashima, A., Ujike, T., Uemura, M., Takao, T., Adachi, J., Tomonaga, T., and Nonomura, N. (2021). Proteomic analysis of urinary and tissue-exudative extracellular vesicles to discover novel bladder cancer biomarkers. Cancer Sci 112(5):2033-2045.DOI: 10.1111/cas.14881
  2. Koba, T., Takeda, Y., Narumi, R., Shiromizu, T., Nojima, Y., Ito, M., Kuroyama, M., Futami, Y., Takimoto, T., Matsuki, T., Edahiro, R., Nojima, S., Hayama, Y., Fukushima, K., Hirata, H., Koyama, S., Iwahori, K., Nagatomo, I., Suzuki, M., Shirai, Y., Murakami, T., Nakanishi, K., Nakatani, T., Suga, Y., Miyake, K., Shiroyama, T., Kida, H., Sasaki, T., Ueda, K., Mizuguchi, K., Adachi, J., Tomonaga, T., and Kumanogoh, A. (2021). Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres. ERJ Open Res 7.DOI: 10.1183/23120541.00658-2020
  3. Saika, A., Nagatake, T., Hirata, S.I., Sawane, K., Adachi, J., Abe, Y., Isoyama, J., Morimoto, S., Node, E., Tiwari, P., Hosomi, K., Matsunaga, A., Honda, T., Tomonaga, T., Arita, M., Kabashima, K., and Kunisawa, J. (2021). omega3 fatty acid metabolite, 12-hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor alpha. FASEB J 35, e21354.DOI: 10.1096/fj.202001687R
  4. Mizuta, H., Okada, K., Araki, M., Adachi, J., Takemoto, A., Kutkowska, J., Maruyama, K., Yanagitani, N., Oh-Hara, T., Watanabe, K., Tamai, K., Friboulet, L., Katayama, K., Ma, B., Sasakura, Y., Sagae, Y., Kukimoto-Niino, M., Shirouzu, M., Takagi, S., Simizu, S., Nishio, M., Okuno, Y., Fujita, N., and Katayama, R. (2021). Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer. Nat Commun 12, 1261.DOI: 10.1038/s41467-021-21396-w
  5. Sugimoto, A., Abe, Y., Watanabe, T., Hosokawa, K., Adachi, J., Tomonaga, T., Iwatani, Y., Murata, T., and Fujimuro, M. (2021). The FAT10 post-translational modification is involved in the lytic replication of Kaposi's sarcoma-associated herpesvirus. J Virol 95(10):e02194-20.DOI: 10.1128/JVI.02194-20
  6. Yasui M, Fukuda T, Ukai A, Maniwa J, Imamura T, Hashizume T, Yamamoto H, Shibuya K, Narumi K, Fujiishi Y, Okada E, Fujishima S, Yamamoto M, Otani N, Nakamura M, Nishimura R, Ueda M, Mishima M, Matsuzaki K, Takeiri A, Tanaka K, Okada Y, Nakagawa M, Hamada S, Kajikawa A, Honda H, Adachi J, Misaki K, Ogawa K, Honma M. (2021) Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMS. Genes Environ. 43, 7.DOI: 10.1186/s41021-021-00179-1
  7. Morii M, Kubota S, Hasegawa C, Takeda Y, Kometani S, Enomoto K, Suzuki T, Yanase S, Sato R, Akatsu A, Hirata K, Honda T, Kuga T, Tomonaga T, Nakayama Y, Yamaguchi N, Yamaguchi N. (2021) Src-mediated tyrosine phosphorylation of PRC1 and kinastrin/SKAP on the mitotic spindle. Sci Rep. 11(1):2616.DOI: 10.1038/s41598-021-82189-1
  8. Iwasaki Y, Sriswasdi S, Kinugasa Y, Adachi J, Horikoshi Y, Shibuya A, Iwasaki W, Tashiro S, Tomonaga T, Siomi H6. Iwasaki Y, Sriswasdi S, Kinugasa Y, Adachi J, Horikoshi Y, Shibuya A, Iwasaki W, Tashiro S, Tomonaga T, Siomi H*. Piwi–piRNA complexes induce stepwise changes in nuclear architecture at target loci. The EMBO Journal. 40(18), 2021.DOI: 10.15252/embj.2021108345
  9. Shoji H, Takahari H, Hara H, Nagashima K, Adachi J, Boku N*. A Phase I study of pevonedistat plus capecitabine plus oxaliplatin in patients with advanced gastric cancer refractory to platinum (NCCH-1811). Future Science OA 7(7): FSO721-FSO721, 2021.DOI: 10.2144/fsoa-2021-0023
  10. Onidani K, Miura N, Sugiura Y, Abe Y, Watabe Y, Kakuya T, Mori T, Yoshimoto S, Adachi J, Kiyoi T, Kabe Y, Suematsu M, Tomonaga T, Shibahara T, Honda K*. Possible Therapeutic Strategy Involving the Purine Synthesis Pathway Regulated by ITK in Tongue Squamous Cell Carcinoma. Cancers, 2021.DOI: 10.3390/cancers13133333
  11. Kinoshita M, Ogawa Y, Hama N, Ujiie I, Hasegawa A, Nakajima S, Nomura T, Adachi J, Sato T, Koizumi S, Shimada S, Fujita Y, Takahashi H, Mizukawa Y, Tomonaga T, Nagao K, Abe R, Kawamura T*. Neutrophils initiate and exacerbate Stevens-Johnson syndrome and toxic epidermal necrolysis. Science Translational Medicine. 13(600): eaax2398-eaax2398, 2021.DOI: 10.1126/scitranslmed.aax2398