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研究業績Achievements

2017年

  1. Sato-Matsubara, M., Matsubara, T., Daikoku, A., Okina, Y., Longato, L., Rombouts, K., Thuy, L.T.T., Adachi, J., Tomonaga, T., Ikeda, K., Yoshizato, K., Pinzani, M., and Kawada, N. (2017). Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling. J Biol Chem 292, 18961-18972. DOI: 10.1074/jbc.M117.793794
  2. Shiromizu, T., Kume, H., Ishida, M., Adachi, J., Kano, M., Matsubara, H., and Tomonaga, T.* (2017). Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics. Sci Rep 7, 12782. DOI: 10.1038/s41598-017-13092-x
  3. Abe, Y., Nagano, M., Kuga, T., Tada, A., Isoyama, J., Adachi, J.*, and Tomonaga, T.* (2017). Deep Phospho- and Phosphotyrosine Proteomics Identified Active Kinases and Phosphorylation Networks in Colorectal Cancer Cell Lines Resistant to Cetuximab. Sci Rep 7, 10463. DOI: 10.1038/s41598-017-10478-9
  4. Ogura, H., Nagatake-Kobayashi, Y., Adachi, J., Tomonaga, T., Fujita, N., and Katayama, R. (2017). TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity. Sci Rep 7, 5519. DOI: 10.1038/s41598-017-05736-9
  5. Kuki, K., Yamaguchi, N., Iwasawa, S., Takakura, Y., Aoyama, K., Yuki, R., Nakayama, Y., Kuga, T., Hashimoto, Y., and Tomonaga, T. (2017). Enhancement of TGF-beta-induced Smad3 activity by c-Abl-mediated tyrosine phosphorylation of its coactivator SKI-interacting protein (SKIP). Biochem Biophys Res Commun 490, 1045-1051.DOI: 10.1016/j.bbrc.2017.06.163
  6. Yamaguchi, N., Shibazaki, M., Yamada, C., Anzai, E., Morii, M., Nakayama, Y., Kuga, T., Hashimoto, Y., Tomonaga, T., and Yamaguchi, N. (2017). Tyrosine Phosphorylation of the Pioneer Transcription Factor FoxA1 Promotes Activation of Estrogen Signaling. J Cell Biochem 118(6), 1453-1461. DOI: 10.1002/jcb.25804
  7. Tomonaga, T.* (2017). Discovery of drug targets by quantitative proteomics and their clinical application. Nihon Yakurigaku Zasshi 149, 123-127. DOI: 10.1254/fpj.149.123
  8. Abe, Y., Nagano, M., Tada, A., Adachi, J.*, and Tomonaga, T.* (2017). Deep Phosphotyrosine Proteomics by Optimization of Phosphotyrosine Enrichment and MS/MS Parameters. J Proteome Res 16, 1077–1086. DOI: 10.1021/acs.jproteome.6b00576
  9. Fujita, K., Kume, H., Matsuzaki, K., Kawashima, A., Ujike, T., Nagahara, A., Uemura, M., Miyagawa, Y., Tomonaga, T., and Nonomura, N. (2017). Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer. Sci Rep 7, 42961. DOI: 10.1038/srep42961
  10. Mizuta, N., Yanagida, K., Kodama, T., Tomonaga, T., Takami, M., Oyama, H., Kudo, T., Ikeda, M., Takeda, M., Tagami, S., and Okochi, M. (2017). Identification of Small Peptides in Human Cerebrospinal Fluid upon Amyloid-β Degradation. Neurodegener Dis 17(2-3), 103-109. DOI: 10.1159/000453358
  11. Morii, M., Kubota, S., Honda, T., Yuki, R., Morinaga, T., Kuga, T., Tomonaga, T., Yamaguchi, N., and Yamaguchi, N. (2017). Src Acts as an Effector for Ku70-dependent Suppression of Apoptosis through Phosphorylation of Ku70 at Tyr-530. J Biol Chem 292(5), 1648-1665. DOI: 10.1074/jbc.M116.753202