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© Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institutes of Biomedical Innovation, Health and Nutrition

研究業績Achievements

2025年

  1. Tanaka Y, Sakahara M, Yamanaka H, Natsume Y, Kusama D, Kumegawa K, Yoshikawa H, Abe Y, Okabayashi K, Matui S, Kitagawa Y, Koshikawa N, Osumi H, Shinozaki E, Nagayama S, Adachi J, Maruyama R, Yao R.  Ribosome biogenesis as a potential therapeutic target in KRAS mutant colorectal cancer. Nat Commun. 17(1):1224. 2025. DOI: 10.1038/s41467-025-67979-9.
  2. Shoji H, Takahari D, Ooki A, Hirano H, Okita N, Nagashima K, Adachi J, Yamaguchi K, Kato K, Boku N. Phase I study of pevonedistat combined with capecitabine and oxaliplatin in patients with platinum-refractory advanced gastric cancer. Sci Rep. 16(1):692. 2025. doi: 10.1038/s41598-025-30367-w.
  3. Sogawa K, Yonekubo R, Shimizu M, Muraoka S, Adachi J, Takano S, Takizawa H, Ohtsuka M, Tomonaga T. Serum fucosylated receptor expression-enhancing protein 5 as a biomarker for early stage pancreatic cancer. Oncol Lett. 30(6):556. 2025. DOI: 10.3892/ol.2025.15302.
  4. Shirai Y, Enomoto T, Takeda Y, Edahiro R, Takahashi-Itoh M, Noda Y,  Adachi Y, Nakayama M, Kawasaki T, Koba T, Futami Y, Yoshimura H, Amiya S,  Hara R, Yamamoto M, Nakatsubo D, Suga Y, Naito M, Masuhiro K,  Matsuki T, Hirata H, Iwahori K,  Nagatomo I,  Miyake K, Koyama S, Fukushima K, Shiroyama T, Naito Y, Futami S, Natsume-Kitatani Y, Ose N, Funaki S, Nojima S,  Shichino S, Yanagawa M, Shintani Y, Nogami-Itoh M, Adachi J, Inoue Y,  ​​Tomonaga T, Okada Y, Mizuguchi K, Kumanogoh A. Serum vesicle biomarkers reflect the disease activity of idiopathic pulmonary fibrosis. J Transl Med. 23(1):1102. 2025. DOI: 10.1186/s12967-025-07011-2.
  5. Iwahara N, Muraoka S, Saito T, Hirano M, Yokokawa K, Tanemoto M, Oda R, Nonaka T, Suzuki S, Adachi J, Hisahara S. Elevated ITGAX/CD11c in CSF-Derived Extracellular Vesicles Reflects Disability Progression in Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 12(5):e200442. 2025. DOI: 10.1212/nxi.000000000020
  6. Yoshii K, Node E, Furuta M, Tojima Y, Matsunaga A, Adachi J, Takaai N, Morita M, Hosomi K, Kunisawa J. Establishment of enterotype-specific antibodies for various diagnostic systems. Sci Rep. 15(1):16814. 2025. DOI: 10.1038/s41598-025-01144-6.
  7. Tomiyama E, Fujita K, Matsuzaki K, Narumi R, Matsushita M, Hayashi Y, Hashimoto M, Kato T, Hatano K, Kawashima A, Minami T, Takao T, Takada S, Uemura H, Adachi J, Tomonaga T, Nonomura N. EIF2S1 in Urinary Extracellular Vesicles as a Novel Diagnostic Marker for Bladder Cancer. Cancer Med. 14(10):e70964. 2025. DOI: 10.1002/cam4.70964.